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lucb1eyesterday at 9:07 PM3 repliesview on HN

Answering the question in the title...

> One study in 2020 found that 95% of asymptomatic patients had some type of "abnormal" finding, but just 1.8% of these findings were indeed cancer.

So a bit less than 1.8% of the time in this study

> Prenuvo's recent Polaris Study followed 1,011 patients for at least one year following a whole-body MRI scan. Of these patients, 41 had biopsies. More than half of the 41 were diagnosed with cancer.

That's 2.0%

Note that this doesn't mean that 1.7~2.0% of people have cancer without knowing it. It could be more:

> A negative scan doesn’t mean you’re disease-free. Some cancers and conditions simply aren’t visible yet or aren’t reliably detected on a one-time full-body MRI."

But also perhaps less, in a way:

> "You're finding something that never would have caused you any problem in your life, and in cancer, we call that overdiagnosis," Vickers says.


Replies

jml78yesterday at 9:24 PM

Yep, I have experience with both. It found cancer for my wife and she was able to treat it immediately. Fully recovered.

It found a weird spot on me that turned out to a pancreatic rest.

The only reason we did the scans were because we were making a significant life decision that we didn’t want to have to backtrack if either got diagnosed with cancer within a year . We knew nothing was guaranteed but we wanted to do some tests.

majorchordyesterday at 9:31 PM

> You're finding something that never would have caused you any problem in your life

Is it though? Isn't it possible you could be early-detecting something serious that is much easier to treat now vs when symptoms appear?

show 2 replies
paulpauperyesterday at 10:28 PM

Yeah a 2% risk of having something which can easily kill you and is very expensive to treat, especially if you're not elderly and still have lots of life ahead of your, is not exactly trivial. I would want to know about this