I'm guessing that you meant this in a semi-humorous and hyperbolic way rather than a mean way, but it would probably be good to review the site guidelines: https://news.ycombinator.com/newsguidelines.html. A comment like this wouldn't need too much to come across as friendly rather than aggressive.

GLP-1s disprove this to an extent. Personal responsibility is based on a fallacy, it’s just brain chemistry.

So give everyone GLP-1s to cast the shadow of personality responsibility (reduction in adverse reward center operations, broadly speaking) through better brain chemistry. Existence is hard, we can twiddle the wetware to make it less hard.

Read my comment more carefully.

If a company put a giant a giant bollard in the middle of the interstate and someone hit it, are you saying that the company bears zero responsibility for that?

Having briefly experienced weight loss drugs - and the bliss of that constant “EAT!” voice in your head just going quiet - I’m pretty convinced most humans have a genuine genetic predisposition to overeating.

And when you zoom out to the population level, the “we’re all autonomous individuals” argument gets a lot shakier. Like yeah, at the individual level you have agency, you make choices, fine. But at scale? We are absolutely at the mercy of whoever has figured out how to tickle our monkey brains in just the right way to get us buying their fattening food.