If anything my guess here would be the master/slave/cable select jumper.
Like, last I looked the Linux kernel still had MFM/RLL support, although I'm not sure that's going to get included even as a module in a modern distro.
IIRC, the Soundblaster 16 driver received a bug fix recently.
IIRC, the Soundblaster 16 driver received a bug fix recently.