This is particularly true of a deep psychedelic experience "inside" with IV Ketamine.
Your own internal processing will still determine how you perceive a perspective change, but specific to this idea in particular, you may for example, within, suddenly find it obvious to think of things as being made of something different than in the outside world reality (and this sort of "change of bases" may reveal some kind of truth not otherwise visible.) You may see something as formed of language instead of molecules and atoms, or vice-versa.