As someone who writes a lot of Scheme, I agree that the math syntax is not good. There have been proposals to add infix expressions (https://srfi.schemers.org/srfi-105/) but nobody seems to want them, or can agree on specifics.
However, code that is mostly function calls is fine for me, since those would have parentheses anyways in C++/Rust/whatever. In that case it makes the language more regular, which is nice for writing macros.
I'd be curious to hear your opinion on wisp (https://srfi.schemers.org/srfi-119/srfi-119.html) and the Readable project (https://srfi.schemers.org/srfi-110/srfi-110.html) which are significant indentation syntaxes for Lisp languages that are still closely related to the AST and allow for easy macro writing.