logoalt Hacker News

ViktorRaytoday at 1:27 PM4 repliesview on HN

The danger of addiction, which is very significant, with opioids doesn’t go away with this modified design.

Unless you’re being sarcastic and referencing the lies the Sackler family used to get OxyContin popular..

That being said it is indeed quite cool that they modified the drug to decrease the respiratory depression.


Replies

wongarsutoday at 1:36 PM

Not just OxyContin. Also Heroin, Meperidine and Tramadol.

We get another "morphine, but safe this time" in pretty reliable 40 year intervals. I guess someone decided OxyContin doesn't count and we are due for another one

show 2 replies
kvgrtoday at 1:49 PM

The chinese factories and cartels can hop on this new formula not.

Nursietoday at 1:35 PM

On the one hand, I'm sure that the post you're responding to is referencing many previous failed attempts at making non-addictive opioid painkillers.

But on the other, non-sarcastic side... if addiction is the only remaining problem with them, should we care that much?

I.E. if both the chronic and acute health risks are gone (which I don't think they are for a second, but follow me along on this little thought experiment)... does it matter quite so much? Clearly addiction, in the abstract, is not exactly a good thing. But if it's not coupled to risk of death it seems to me it would be a great thing to transition addicted people to, and take away some of the urgency of the situation.

show 6 replies
fredgrotttoday at 1:31 PM

and the fun fact, the other new drug targeting the mid-receptor of acetyl-choline that functions like mu-opioid receptor also has the same exact addiction problems.