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DesaiAshutoday at 3:42 PM1 replyview on HN

Adjacent medicines have seen major improvements: eg Ketamine was a significant improvement from PCP (notably, less psychosis and safe enough to use off the battlefield / with children)

“Removing the worst and most fatal danger” is a laudable goal with Fentanyl given the absurd rate of ODs


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at-wtoday at 5:13 PM

As have the opioids buprenorphine and Suboxone (buprenorphine/naloxone), which are genuinely useful treatments for addiction and have much lower risks of abuse.