alt Hacker NewsWhat a headache!
My practical view is to avoid spaces in directories and filenames, but to write scripts that handle them just fine (using BASH - I'm guilty of using it when more sane people would be using a proper language).
My ideological view is that unix/POSIX filenames are allowed to use any character except for NULL, so tools should respect that and handle files/dirs correctly.
I suppose for your usage, it'd be better to put the virtualenv directory into your path and then use #!/usr/bin/env python
For the BSDs and Linux, I believe that shebang are intepreted by the kernel directly and not by the shell. /usr/bin/env and /bin/sh are guaranteed by POSIX to exists so your solution is the correct one. Anything else is fragile.