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zeronightyesterday at 7:40 PM4 repliesview on HN

The part I can't get past, where would you source live human brain cells?

Does anyone have insight into how you would even start to source or grow/create the cells?

Also the machines look very organic and clearly have to keep the cells alive. Do they have to change them out every so often?


Replies

drzaiusx11yesterday at 8:05 PM

There's a number of "immortal" human cell lines dating back to as far as the 1950s (you may have heard of Henrietta Lacks? [1] and the immortal HeLa cell line).

Today there are several immortalized neuron cell lines used in research to model neuronal function, like HeLa but of neuron type obviously, that are also typically derived from tumours (e.g., SH-SY5Y, PC12) or immortalized via genetic modification (e.g., v-myc) like CTX0E03 [2] which was designed to allow for continuous growth in the presence of particular reagents.

1. https://en.wikipedia.org/wiki/Henrietta_Lacks

2. https://www.prnewswire.com/news-releases/reneuron-announces-...

show 1 reply
hessarttoday at 3:29 AM

ahem

If you're in the US, you can buy human neurons online at sciencellonline.com/en/human-neurons/

fenykepyesterday at 7:56 PM

I think the Thought Emporium youtube channel has some explanatory [videos](https://www.youtube.com/watch?v=bEXefdbQDjw) of the whole process. I couldn't wrap my head around the thing tho.

lateforworktoday at 1:46 AM

They are lab grown.