Sugar is 50:50 fructose:sugar and "high"-fructose sugar is 55:45. The slight difference in fructose:sugar between the two is not significant in terms of health outcomes, unless you mean sugar in general.
It's partly the pervasiveness of that product because it's in fking everything in the US at least. Why is it in BREAD? https://www.thedailymeal.com/1306301/unhealthiest-store-boug...
It's also the crazy amounts: we're accustomed to high levels of sweetness. Like 40g sugar in a can of soda.
I can't make sense of your comment, but whatever you're trying to get at is wrong: Table sugar is sucrose. Corn syrup is mostly glucose and contains no fructose. HFCS is commonly produced at 42% and 55% fructose formulations. I don't think HFCS is meaningfully more or less harmful than any other sugar, but chemically there's a significant difference.