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MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

64 pointsby carlos-menezestoday at 11:16 AM69 commentsview on HN

Comments

tim-projectstoday at 12:53 PM

I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans.

It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them.

These experiments need a control where they just take the drug and they don't have medical staff around.

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throwaway12poltoday at 11:24 AM

Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!

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steve-atx-7600today at 12:59 PM

I’d be afraid of a treatment like this where you’re sort of different after one treatment. From experience taking ssris, I took one one that worked so well that I had to stop taking it because it removed stress to the extent that I wouldn’t get to class on time or get my homework done before deadlines. Eventually I found a medicine that worked for me. But, if there’s a “before” vs “after” one shot treatment, you have to hope the new you is the one you want assuming you could be stuck there permanently.

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kykattoday at 11:50 AM

It seems like every few weeks there's an article on how drugs are amazing hitting the front-page.

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butliketoday at 7:21 PM

At the risk of sounding like an imbecile, can I ask why LSD-25 can't be the pharmaceutical form of LSD?

analog8374today at 11:29 AM

"Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves. Here's Tom with the weather."

-Bill Hicks

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khelavastrtoday at 12:42 PM

This reflects a longstanding...essentially conspiracy...to suppress attention to 5HT2A-based neural regulation because it sheds such poor light on SSRIs

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kunleytoday at 12:01 PM

It is tragically funny to consider linking quietness of mind with LSD. It is everything but quiet

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OutOfHeretoday at 12:26 PM

Of course they want to repackage a cheaply synthesized substance at 100-1000x the costs even though the original likely works just as well. That's pharma for you.

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Rygiantoday at 11:33 AM

The "surprising way" is by using a derivate of LSD.

I'd argue that the surprise is rather on this: "In clinical trials, a single dose significantly outperformed standard treatments, offering hope to those who have found little relief elsewhere."

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the-golden-onetoday at 12:54 PM

Clickbait

PowerElectronixtoday at 12:19 PM

"Side effects were mild or moderatr and included hallucinations..."

Yeah....

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