I guess it depends on how you define life, and whether we'd even recognize it when we see it, assuming we're looking in the right places.
I'd also imagine that any type of chemistry that harvests energy from the environment is liable to find itself as a food source at the bottom of the food chain now that earth is teeming with life.
I think that self-replication, and ability to harvest chemicals and energy from the environment to make more of what you're built of, is the point of complexification of chemistry that is best considered as the most primitive form of life. From there you can go on to things that are capable of encoding structure and more complex chemical factories.
I suppose one signature of these earliest type of "emergent life" chemistries would be localized concentrations of things like these nucleobases that we know are the building blocks of life as we know it, but there may be other types of self-replicating chemistries that emerge too, that don't lead anywhere.
> I think that self-replication, and ability to harvest chemicals and energy from the environment to make more of what you're built of, is the point of complexification of chemistry that is best considered as the most primitive form of life
Once there are forms that harvest and self-replicate, however, its expectable that there will be forms that delegate those features to others, like viruses. Cellular machinery that is required to implement those feature is not free, so parasitic forms would have survival advantage.