I did contract work for a company who made heavy investments into Notes-based applications. The replication capability was super cool. We would setup a new client computer on the corporate LAN, synchronize them to the various Notes databases they needed, then send the computer out to field service reps who would use the computers mostly offline. They updated over a pool of dial-up modems at headquarters. They would run mostly overnight, with the field service reps dialing-in before bed and leaving it to run until it automatically disconnected. Later they used a VPN and dial-up ISPs. It worked astoundingly well.

Their developers moved thru the organization over a period of years making Notes databases out of every paper form-based workflow process they could get their hands on. I lost touch with them and they were acquired by another company, ultimately. I'd love to know what happened to all those custom applications living in Notes. It's hard to think of a platform that could have easily replaced it-- particularly the offline sync / local first portion.