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mdeveretoday at 2:53 PM4 repliesview on HN

Very strange how HN elevates news about random drug candidates at very early stages of development.

There is a very active landscape of people developing/validating 'biomarkers' for neurological and psychiatric disorders and developing drugs specifically for those populations with the biomarker present; this news is far from extraordinary.

The real news is when these reach FDA approval.


Replies

derektanktoday at 3:06 PM

Identifying a biomarker for a psychological condition, particularly one like schizophrenia which is hugely disruptive for individuals affected and has a seemingly random onset around early adulthood, is significant in its own right even if it doesn’t lead to a pharmaceutical intervention. It could help identify new risk factors, potential non-pharmaceutical interventions like life style changes, and maybe even identify people who are at risk of developing schizophrenia and preparing them for its onset before their first hallucination and avoiding a downward spiral.

lich_kingtoday at 3:00 PM

Disproportionately many geeks have very strong opinions about psychiatry, probably because we have a lot of people who consider themselves neurodivergent, as well as plenty of folks who experiment with drugs.

tokaitoday at 3:58 PM

Absolutely nothing strange about following research, and sharing and discussing has nothing to do with elevating.

What is actually weird is how often users here makes it an issue when research papers on novel drugs are shared here.

lenerdenatortoday at 3:21 PM

Given how debilitating schizophrenia can be, and how compromised the current treatments are - hey, you don't mind making uncontrollable strange expressions on your face forever, do you? - things like this give hope, even if it's just a little bit.