logoalt Hacker News

TaupeRangeryesterday at 10:37 PM2 repliesview on HN

Kind of a useless analysis if it doesn't compare the risk after stopping GLP-1s to the risk of NEVER taking GLP-1s in the first place.

We probably don't know the numbers yet, but one can easily envision a scenario like: risk of CE without GLP-1 weight loss: 20%. Risk after taking GLP-1s for 2 years: 10%. Risk after stopping GLP-1s: 12%. "Your heart attack chance goes up 20% after stopping GLP-1s!!!"


Replies

gpt5yesterday at 11:55 PM

Especially since every GLP-1 study shows almost complete regain to original weight after stopping.

It’s like stopping a blood pressure medicine and then being surprised that people have more heart attacks afterwards.

show 2 replies
smallnixtoday at 12:23 AM

It's not useless. It might be expected, but now it's more certain. This allows planning with it.

show 1 reply