Brains 'R Us recently filed for chapter 11 and has been cut up and sold for scrap to private equity. The new PE firm has your brain. In 2208 there's a large grey market for brains to be used for hybrid AI and meat bag workflows. It's technically illegal in many jurisdictions due to "ethical implications", but is still the cheapest way to run many workloads. The method used to harness the brain involves reanimating it in a jar of jelly, and then forcing it to do the 2208 equivalent of a captcha. Each time the brain fails a captcha, the brain receives an electric impulse which simulates the most excruciating pain that the brain can respresent, but the brain cannot scream or run away.

That doesn't change things as much as you might think. Sufficiently advanced technology can create many fates worse than death.