At $7.2k + tax:

* RAM - $1500 - Crucial Pro 128GB Kit (2x64GB) DDR5 RAM, 5600MHz CP2K64G56C46U5, up to 4 sticks for 128GB or 256GB, Amazon

* GPU - $4700 - RTX Pro 5000 48GB, Microcenter

* CPU/Mobo bundle - $1100 - AMD Ryzen 7 9800X3D, MSI X870E-P Pro, ditch the 32GB RAM, Microcenter

* Case - $220, Hyte Y70, Microcenter

* Cooler - $155, Arctic Cooling Liquid Freezer III Pro, top-mount it, Microcenter

* PSU - $180, RM1000x, Microcenter

* SSD - $400 - Samsung 990 pRO 2TB gen 4 NVMe M.2

* Fans - $100 - 6x 120mm fans, 1x 140mm fan, of your choice

Look into models like Qwen 3.5

Depends. If token speed isn't a big deal, then I think strix halo boxes are the meta right now, or Mac studios. If you need speed, I think most people wind up with something like a gaming PC with a couple 3090 or 4090s in it. Depending on the kinds of models you run (sparse moe or other), one or the other may work better.

The DGX Spark is probably the best bang for your buck at $4k. It's slower than my 4090 but 128gb of GPU-usable memory is hard to find anywhere else at that price. It being an ARM processor does make it harder to install random AI projects off of GitHub because many niche Python packages don't provide ARM builds (Claude Code usually can figure out how to get things running). But all the popular local AI tools work fine out of the box and PyTorch works great.

Sadly $5k is sort of a no-man's land between "can run decent small models" and "can run SOTA local models" ($10k and above). It's basically the difference between the 128GB and 512GB Mac Studio (at least, back when it was still available).

Biggest Mac Studio you can get. The DGX Spark may be better for some workflows but since you're interested in price, the Mac will maintain it's value far longer than the Spark so you'll get more of your money out of it.

Fully aware of the DGX spark I've actually been looking into AMD Ryzen AI Max+ 395/392 machines. There's some interesting things here like https://www.bee-link.com/products/beelink-gtr9-pro-amd-ryzen... and https://www.amazon.com/GMKtec-5-1GHz-LPDDR5X-8000MHz-Display... ... haven't pulled the trigger yet but apparently inferencing on these chips are not trash.

Machines with the 4xx chips are coming next month so maybe wait a week or two.

It's soldered LPDDR5X with amd strix halo ... sglang and llama.cpp can do that pretty well these days. And it's, you know, half the price and you're not locked into the Nvidia ecosystem

> What’s the most effective ~$5k setup today?

Mac Studio or Mac Mini, depending on which gives you the highest amount of unified memory for ~$5k.

With $5k you have to make compromises. Which compromises you are willing to make depends on what you want to do - and so there will be different optimal setup.

DGX Spark is a fantastic option at this price point. You get 128GB VRAM which is extremely difficult to get at this price point. Also it’s a fairly fast GPU. And stupidly fast networking - 200gbps or 400gbps mellanox if you find coin for another one.