> An example I've frequently run into is where I forget a closing curly brace. The error is reported at the end of the file, and gives me no advice on where to go looking for the typo. The location should be obvious, as it's at exactly the point where the indentation stops matching the braces. But the parser doesn't look at indents at all, so it can't tell me that.

That's somewhat a quality of service issue though. Compilers should look at where the braces go out of kilter vs indentation and suggest the possible unmatched opening brace.