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CuriouslyCtoday at 2:43 PM1 replyview on HN

This was a follow-on to a study of nurses showing coffee drinkers have lower all cause mortality.

Caffeine has been shown to exert effects via adenosine receptor antagonism and influence on cAMP & AMPK pathways. These same pathways are implicated in a lot of issues with aging. Caffeine also has some anti-inflammatory properties and Coffee beans are a strong anti-oxidant though I don't really think that matters much.


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johnisgoodtoday at 2:57 PM

> Caffeine has been shown to exert effects via adenosine receptor antagonism and influence on cAMP & AMPK pathways. These same pathways are implicated in a lot of issues with aging.

That is like saying biological pathways are implicated in aging (because you said "pathways").

In any case, adenosine receptor antagonism has a pretty weak link if any to aging.

Additionally, we say that about virtually everything that is herbal, that it has anti-inflammatory properties. You are right, it does not matter at all.