In security? Not really, unless you are doing immutable deployments with rootless containers, no shell access, which at the end of the day isn't UNIX any longer.
And which Linux exactly? Plus unless you're doing C or C++, most likely aren't using those APIs.
Anyway, the differences of bare metal servers don't matter in the days of cloud where the actual nature of the kernel running alongside a type 1 hypervisor hardly matters to userspace.