Do you have the brightness on your monitor set really high or something?
I frequently use macOS on a projector, it doesn't quite fill my wall floor to ceiling but it comes close. I don't use full screen often, but I do it occasionally as a focusing strategy, and it's fine.
Projectors are way easier on the eyes than monitors though.
You're shining a bright light on a wall, which you are looking at.
With a monitor you are shining a bright light at your face, while staring directly at the lightbulb!