https://en.wikipedia.org/wiki/AlphaFold ...

we've had AlphaFold for a while. it's not a novel that we have ML solutions that can find, erm, novel solutions.

however, by and large, most LLMs as typically used by most individuals aren't solving novel problems. and in those scenarios, we often end up with regurgitated/most common/lowest common denominator outputs... it's a probability distribution thing.