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gwwyesterday at 12:08 PM2 repliesview on HN

I haven't really read the studies but shouldn't they have negative controls to negate these effects? Wouldn't that let the author's correct for a baseline contamination level in the lab?


Replies

throwup238yesterday at 12:31 PM

That was the difficulty with DNA: how do you make that control if everything is contaminated and minor variations in protocol (like wafting your hands over the samples one too many times) changes the baseline?

It took years to figure out proper methods and many subfields have their own adjusted procedures and sometimes even statistical models. At least with DNA you could denature it very effectively, I’m not sure how they’re going to figure out the contamination issue with microplastics.

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codebjeyesterday at 12:09 PM

On the one hand, hundreds or perhaps thousands of studies might be wrong. On the other hand, this one might be wrong. Who's to say?

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