Sure, if you have full rights. I run my computer for weeks at a time without rebooting. However, at my employer, where there is very little control, it’s a different story.
About two weeks ago, some Adobe Acrobat update introduced a hang that results in “Acrobat won’t open.” Open Task Manager and there’s four to eight stuck processes. Kill them and it works again most of the time, but once in ten it simply doesn’t recover.
Adobe acknowledged the issue to someone on my team. There’s no need for me to understand further; telling the user that a reboot will solve it is prudent advice. It’s on Adobe to fix it. You made assumptions about the environment where I tell people to reboot without understanding the conditions and I have an immediate real world case demonstrating why your statements don’t apply.