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Finbarrtoday at 6:52 PM0 repliesview on HN

MS treatments tend to take 3 forms:

- immune reset (sledgehammer that can “cure” diseases like MS but with many side effects and potential complications)

- immune suppression (super effective but with increased risk of infections and blunts vaccines)

- immune redirection (less effective but doesn’t mess up your immune system so badly).

It’s only in the last ~10 years that super effective treatments that can stop ~99% of lesion progression have existed- Ocrevus and Kesimpta. These are anti CD20 disease modifying therapies that destroy all your B cells. The memoir of Dr. Stephen Hauser- “The Face Laughs While The Brain Cries”- provides a fascinating insight into the development of these treatments over the last ~40 years of his career.

There are active trials of newer types of treatment and a lot of progress is being made in the MS space. It used to be a “death sentence” disease but is quite manageable for many sufferers now. It’s different for every individual and I wish the blog author good health.