Clojure on the JVM adds niche-language overhead to old deployment pain, so you get bleeding-edge bugs and mid-90s release rituals in the same stack. If you want to onboard new hires to Clojure expect to spend time on editor config and build tooling before they can even trust a stack trace. You still inherit Java's GC quirks without much type-driven tooling.
Typically you're either deploying via a container, in which case there's no more overhead than any other container deployment, or you're deploying directly to some Linux machine, in which case all you need is a JVM - hardly an arcane ritual.