I'm not sure they really feel significant guilt.

I think they're reflexive people and for Andreessen the long period where he was massively invested in the shadiest crypto companies required pushing a culture of conformity.

A lot of Andreessen's investments were essentially pyramid schemes and the greatest threat to those investments was intellectual honesty & introspection.

Under that pressure from him and others a lot of the tech world shifted towards being more tribal. We saw a huge shift away from intellectual honesty and critiquing actions & ideas on their merits to instead a culture of fiercely defending founders and relentless hype.

I also believe that's why they shifted towards the political rightwing, because the more tribalist approach is presently rewarded on that side.