The GP said more with LLMs than people - not no interactions at all with people and not preferring machines to people. I don't think it is that hard to spend more time talking with LLMs than people if you work in tech and I don't think that takes away from one's life meaningfulness.
Yes, this is called alienation of the work place and it has been discussed since the 1800s. Maybe tech workers will realize that their employers are literal enemies of humanity rather than their friends.
Employers want to mechanize humans and they'll force it even if it makes everyone miserable for their entire, short, lives.
Amazon is a good example of this.