Unshielded circuits are basically radiation detectors. Even here on planet Earth bitflips are an underappreciated source of unreproducible bugs.
A bit flip in an index variable, a pointers or in native code can send the CPU on a wild goose chase around memory.
To add insult to injury, applications like browsers use JITs, which generate and execute large amounts of native code on the fly, making them even more vulnerable for this kind of fault.
The same issue arises from overclocking, inconsistent power sources, and from damaged RAM cells, but those problem sources can presumably be dismissed on a vehicle with pristine, well-made hardware during a short hop to the moon and back.