Personally, the last holdover is Ableton. Last time this came up, bunch of people pointed me to https://github.com/BEEFY-JOE/AbletonLiveOnLinux which has since then been marked as archived, and I'm still unable to run Ableton 12 properly on Linux via WINE, even though I've probably spent too many man-hours on getting it to work...
I'm still eagerly awaiting the day though, any day now surely.