I dont this wisdom can be applied generically. Lets consider your example, if leader or founder comes across the fact that a river is getting polluted whether it makes profit or not, they will not take that decision as it would impact longer term.

What you are mixing is founder led business vs ceo led business. CEO often takes a short term view, when stakeholders are PE Firm, wall street, short term gains are prioritized. But for, a long term investor, would not incentivize you to take calls that would harm in long run.

What could be wrong is that, you wouldnt know all the consequences and causality of your decisions and thats very human thing in my opinion.