Afaik, Polymarket removes predictions that break CFTC's regulations (this includes assassinations, etc., at least in the US). They basically provide no value unless you're an insider, but they do tend to be leading indicators so it might inform some decisions (like: should you keep your money in oil?) that could be contingent on Polymarket predictions.
If I'm reading the order book correctly, right now you can "win" $474,746 on Polymarket with a $4,000 bet if Trump "ceases to be the President" by April 30
https://polymarket.com/event/trump-out-as-president-by-april...
which is effectively an assassination market on him. And there other such crowd-sourced hits on other heads of state.