It depends on how your timers are implemented. If they are implemented as a "rendez-vous" absolute date (as in UTC for instance - not in local time unless you want to add "eastern eggs" related to daylight saving time...), this will cause bugs. If you implement your own in-game monotonic clock that you can stop, it should be ok.
>If they are implemented as a "rendez-vous" absolute date
Do people actually do that? What's the plan for when the user sleeps their machine? All the events just inexplicably happen all at once when they wake it?