This is why I suspect that GLP-1 agonist medications have the potential to cause a cascade of negative consequences for the health of some people. One of the mechanisms is slowed gastric emptying which leads to decreased motility of the small intestine as a side effect. They do tell people to drink more water to counteract this. It just seems like trading one set of problems for another so hopefully doctor and patient will carefully weigh the benefits versus the risks. We shall see.