The US doesn’t have air supremacy in Iran. We have air dominance, but shoulder mounted infrared guided (bypasses stealth paint to go after engine exhaust) AA is still taking out the occasional F35 and A10.

RU/UA is special because RU completely screwed up the first 3 weeks of the war (likely because of the culture of sycophancy Putin has, similar to Trump) and was driven out of central UA. Russia is too proud to admit they lost and UA wasn’t allowed to attack into RU territory until their suppliers (US, EU) were confident RU wouldn’t nuke us in retaliation. Now UA is busy dismantling RU’s economy and war making industry. Ultimately it’s not comparable to any other war of our lifetimes for several reasons.

UA drone factories aren’t in large industrial buildings. They have hundreds of office / home locations where the parts are printed / assembled. RU largely has a very few mega military vendors who make drones / missiles and they have consolidated their efforts in a few (now vulnerable) locations.

F35 capability is excellent for preparing the battlefield, such as the first few hours when softening up air defenses.

But don’t underestimate how much all countries are learning from watching RU/UA or US/Iran. Drones will continue to evolve to meet the gaps in affordable interception, affordable anti-5thGen aircraft, etc. UA now has armed land, sea, and air drones and each has variants like scout, bomber, interceptor, etc. we will continue to see specialization and comparative advantage evolve in the space.