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bennettnate5yesterday at 2:14 PM3 repliesview on HN

I have a family member who has discovered through gradual process of elimination that she gets migraines from MSG, aspartame and yeast extract. "just sodium headaches" doesn't really apply to her case; simply chewing a piece of gum that has aspartame, or eating a piece of meat cooked with MSG in her salad is enough to trigger them. I agree in the general sense with your comment and the article that there's no widespread danger to public health from these additives, but it doesn't mean there aren't still individuals whose health gets messed up (including legitimate headache or migraine symptoms) by these additives.


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ch4s3yesterday at 2:30 PM

> discovered through gradual process of elimination that she gets migraines from MSG

This is definitely not true. There is no biological pathway that can do this. MSG is nearly identical to the glutamic acid in other foods. If it were true they'd be unable to tolerate parmesan cheese, soy sauce, aged meats, tomatoes, mushrooms, and seaweed.

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cestithyesterday at 2:52 PM

Aspartame is also a trigger, but the fact that one person has multiple triggers doesn’t mean they are related at all.

Now you’re right that MSG is more than sodium. Sodium can be a headache trigger, including migraines. Glutamate is also a migraine trigger and a fairly common one. It doesn’t happen to be one for me. However, it is a neurotransmitter that is involved in pain signaling. It’s understandable how it could easily trigger a migraine or make the pain worse.

Some triggers for some people actually help other people with migraines, like caffeine. Migraines are such an incredibly complex topic that there are medical specialists for them. Mine can be fairly debilitating, but are rare enough I don’t qualify for most prescriptions. So I definitely understand how trigger management and symptom management are a big deal.

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JCattheATMyesterday at 2:30 PM

Sounds like an allergy.

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