On a quick read of the docs I'm a bit worried Quarkdown doesn't have the right evaluation model for the job. Text layout typically iterates to a fixed point, because adjusting the layout of one part of the document can throw out layout at another part, require another layout pass and so on. Typst has the concept of context[1] for this. I didn't see anything in Quarkdown that seemed similar, though perhaps I missed it.

I switched from pandoc / md / LaTex to Typst for my book[2], and have been very happy with it. Programming in a modern language is nice, and Typst is much faster than pandoc + LaTex.

[1]: https://typst.app/docs/reference/context/

[2]: https://functionalprogrammingstrategies.com/