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rpmismstoday at 12:54 AM1 replyview on HN

I'm not trying to make a complete argument, I'm trying to raise a flag. This issue is not well-studied and has very large corporate sponsors who would like to keep selling Roundup-Ready™ crops. One particular measurable function is inhibition of the shikamate pathway in many different bacteria (the majority of the volume of your gut flora is affected).

Here's a decent paper that shows an adverse effect: https://pmc.ncbi.nlm.nih.gov/articles/PMC10330715/

I understand that this is the realm of crunchy weirdos, but thinking holistically doesn't mean you need to lobotomize yourself.

Here's another paper examining some brain effects of chronic gut inflammation, which could be reasonably inferred as a potential consequence of long-term glyphosate exposure: https://pmc.ncbi.nlm.nih.gov/articles/PMC10661239/


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tptacektoday at 1:03 AM

You haven't raised a flag! You've observed (and cited a paper that shows in mouse models under relatively high human dosages) that glyphosate can impact certain gut bacteria species. That's plausible! But all sorts of things do that, and you haven't presented evidence that connects that to an adverse human health outcome. In particular: you haven't cited a source showing glyphosate is causative of gut inflammation.

"It impacts the gut biome" isn't a get-out-of-jail-free card for these arguments; if it were, you could knock down all sorts of things, including specific diets (and most abrupt changes in diet).

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