Interesting word soup. Ultimately, no, you cannot build a valid representation of the universe from nothing and you need observation and validation. You can presupposition whatever you want when you are talking about unproveable models, but it says more about you than the universe. Until we have a reason to think that there is a "why", discussing what it is is completely unnecessary and futile because 1) it does not change anything about our understanding or the predictions we can make, and 2) it is not something we can observe, measure or prove.
You don’t need any observations at all to build up a complete knowledge of the entire universe. Hegel showed this