For a very long time I thought Time Machine had become flaky, and I'm sure it's partially to blame, but with my current setup I've literally never observed it corrupt a backup and have to start over.

Before I was using one of the common Synology consumer NAS boxes that are often recommended. The NAS didn't report any errors with the drives or its own hardware, but at least once a month TM would glitch on at least one of my home laptops.

My new setup is an Asus FLASHSTOR 12 Pro Gen2 FS6812X. For a year now it's been running without a single apparent TM glitch while backing up multiple personal laptops and my work laptop. Sometimes I'm plugged in and sometimes I'm backing up over WiFi, but it's always worked.

I tried various recommended settings for the Synology and nothing helped so I strongly suspect that the Synology network protocol(SMB, AFP, etc.) implementations were either buggy themselves or at least not compatible with quirks in Apple's implementations. Synology->Asus fixed all my TM problems instantly and seemingly permanantly!