Some of the plugins for it are pretty interesting. We have a Brother embroidery machine in our work Makerspace, and it ends up there's an Inkscape plugin (called Inkstitch) to create command files for the machine. It's like working with a slicer for 3d printing, but more about changing thread than filament, plus how stitches should be oriented and such.
My wife makes extensive use of inkstitch and loves it.
Yes! I use an Inkscape extension to send my own designs to a vinyl cutter that works perfectly well but has LONG since stopped being supported by its manufacturer or any other closed-source tools.
The extension is inkscape-silhouette (https://github.com/fablabnbg/inkscape-silhouette) and is apparently being maintained by a makerspace in Germany.