The Signetics 2650 found its way into a bunch of arcade games by lieu of British company Century Electronics. I have a conversion kit of theirs installed into a Donkey Kong Jr. board, which outright replaces DK Jr.'s Z80 with a daughterboard containing the CPU. Always wondered why they chose that in particular, it's not a very common chip, and just using the Z80 that was there and replacing the ROMs was the more common option for conversion kits like that.