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keepamovintoday at 2:57 AM1 replyview on HN

No, policy wise I appreciate you getting into the nuance, but I feel like you take the argument to polar extremes (with an attitude of confident, final certainty), when the expected outcome is across the middle. This smells more like ideology than practicality.

> These discussions always end up …

Before your comment i wouldn’t say anyone is lacking curiosity here. Tho your comment about fixing into a stereotype, seems the example of itself. I think it’s better to listen and discuss than assume the futures settle into a mischaracterization that you’ve already decided. That doesn’t seem very useful - except for ideology…

On the toxicity side, do you have any studies to cite? I wasn’t aware of toxicity, but it’s plausible.

Big picture tho, I’m not an expert in drug policy. It just sounds like a logical way to reduce harm overall. Reduce harm overall - worth repeating; on average, create a better society.

The conceivable parties who would lose out are: government funded agencies charged with fighting drug crime because their caseload and budgets would probably decrease; and on the other side the cartels and dealers. Although what seems to happen with the latter is once something is legalized, the supply chains morph into legitimate businesses somehow.

I still think it would work. I’m not convinced by what you said. Thank you tho


Replies

cyberaxtoday at 3:45 AM

> On the toxicity side, do you have any studies to cite? I wasn’t aware of toxicity, but it’s plausible.

A typical therapeutic dose of amphetamines is around 20mg, topping at around 60mg for serious narcolepsy. Recreational doses can go up to around 1000mg for long-term users with 360mg as the median: https://pubmed.ncbi.nlm.nih.gov/40385390/

That's the area of crazy toxic side effects just from vasoconstriction. Never mind direct effects on the brain.