alt Hacker NewsSaliva divinorum is inherently dysphoric due to its agonism of the kappa opiod receptor. For a different cheap legal drug that affects serotonin and the NMDA receptors like ibogaine does, there's always off label use of dextromethorphan (cough medicine)!
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Trasmatta • today at 2:56 PM
DXM is also the active ingredient in the antidepressant Auvelity (combined with bupropion)
Lot of interesting studies and anecdotes on its efficacy as an antidepressant
Really difficult to find a cough syrup with only high amounts of DXM and nothing else. All the brands changed their recipes in the late 90s.