Yeah, but nicotine itself can still be problematic for mental health. It really depends on what you consider an "adverse problem".

I had been using the pouches for a couple of years now, and the unbearable anxiety from its nonstop use caused me to slow it way down. I went from a can a day to less than a can a week. I had already quit all other forms of nicotine before the pouches. What a wild ride.

Because the anxiety is unlikely to just be from nicotine alone, I also got myself into somewhat better shape to cope. Maybe some anxiety is healthy if it drives better choices, but it still feels awful. I'm now glad with my current state, but I would not recommend this path to here.