I have a 128G mac studio and even 397B was a happy surprise to me due to its high quantization resilience.

I've created a 2.54BPW quant that fit on my hardware with 128k context, 20 tps tg and 200tps pp, while maintaining high scores on many benchmarks: https://huggingface.co/tarruda/Qwen3.5-397B-A17B-GGUF/discus...