Human cognition is poorly understood and much more complex than it seems.

For an example, look at some of Julia Mossbridge's work.

If even a small part of her work is true and valid, it points to something far outside our current framework.

You don't need to go as far afield as Mossbridge, though - that's an extreme example. Pretty much any modern neuroscience will make you question a lot of assumptions, at least it did for me.