I like React.

I made sure that all of the interactions in our app that don't require a server round-trip are instant, without any annoying undead skeletons and animations. This works really well because we keep most of the data in RAM on the client, with IndexDB as the backing store and a custom synchronization protocol.

I avoided the "server-side rendering" out of a general distrust of "magic" solutions that do everything for you.

React itself is also really straightforward as a mental model of rendering.