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groby_byesterday at 11:13 PM1 replyview on HN

It's not quite that clear-cut. Franklin was pretty clear on the helical structure in both research notes and papers, but she didn't quite nail the overall structure (2 strands with opposing winding, complementing bases).

Fundamentally, she suffered the curse of the experimental scientist - waiting for actual data before being willing to build a model. Watson & Crick postulated ahead based on partial data.


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dnauticstoday at 3:09 AM

> Franklin was pretty clear on the helical structure

the type of diffraction her lab was doing only makes sense on helical structures. it being helical was already kind of? established -- linus pauling was contemporaneously working on some sort of alpha-helix inspired single helix model.

watson and crick immediately recognized the position of the diffraction spots fit the distances suggested by their chemical modeling of a, t, c, g, which franklin was not able to do since she hadn't made a structural prediction.

> postulated ahead based on partial data

not quite. if you know that a t c and g are the raw chemicals made, you can make a (possibly even literal) model and say, "this ball and stick model predicts diffractions here".

this is arguably better science than waiting for data and fitting a model to the data, falsifiability and all that.