I don't mind a GUI (as long as it isn't an obnoxiously large ribbon or anything) - but if I'm doing work my input device is the keyboard. I don't want to interface with software through moving a mouse pointer when I can just tell it what to do with a few keystrokes.
Xerox PARC REPL sytle, and better you can get the inline graphics for free, as there is no need to emulate a teletype.